Publications

Scientific Essays, Research Commentaries and Responses published by Interstitium.

4 publications
graphical Abstract: The way out must remain open
Conceptual Paper

The Way Out Must Remain Open

Daniel A. Raus de Baviera1
Interstitium · Volume 1 (2026) · #04
Published 12 November 2026
Theory, Concepts & Frameworks

Preparing for a technological future can make that future harder to reconsider. When applicants, employers and universities adapt to what they expect others will soon require, each decision may be reasonable. Together, however, they can create dependencies that leave later, better-grounded judgement without practical effect. This paper examines that mechanism, collective anticipatory self-binding, through hypothetical models of AI adoption, archaeological evidence from the Fremont complex and research on human–automation interaction. It asks when the loss of opportunities for correction requires justification, and what keeps technological commitments revisable. Drawing on published sources, it distinguishes the formal possibility of reviewing a decision from the practical capacity to change it. It then develops five dimensions for assessing revisability: scope, uncertainty, possible adverse consequences, substitutability and the power to secure correction.

Scientific Essay

More Herbal Products, Less Herbal Medicine?

Daniel A. Raus de Baviera1 Inmaculada C. Meca-Sáez2
Interstitium · Volume 1 (2026) · #03
Published 15 October 2026
Phytochemistry & Phytopharmacology

More herbal products on the shelves do not necessarily mean more new medicines for patients. The difficult step is turning botanical knowledge into a reproducible preparation with demonstrated clinical Benefit and making that development economically viable. This Scientific Essay examines that bottleneck through observations from the 2026 GA Congress in Reims, selected product histories and regulatory examples from Europe and beyond. It asks whether existing approval routes can support sustained development of new complex preparations, particularly by smaller companies, and what would make those routes more viable. Drawing on published sources, it distinguishes limited innovation from the loss of existing products or effective treatment options and develops a reasoned scenario for the future of European phytotherapy.

Scientific Essay

When May Medicine Treat Distinguishable States as Equivalent?

Daniel A. Raus de Baviera1
Interstitium · Volume 1 (2026) · #02
Published 24 August 2026
Systems Biology & Organisational Biology

Medicine can distinguish ever finer biological and clinical states. Yet the decisive question is not simply what medicine can distinguish, but what it must distinguish to make sound decisions. This Scientific Essay develops a framework for determining when treating distinguishable states as equivalent is sufficient for the decision at hand—and when doing so conceals differences that alter benefit, harm, or access to care. Drawing on examples from precision oncology, pharmacogenomics, diagnostic testing, non-inferiority trials, and biosimilar regulation, it synthesises published evidence and reports no new empirical data.

Research Commentary

A Mediterranean Shrub Long Linked to Fire May Also Be Shaped by Runoff

Daniel A. Raus de Baviera1,2
Interstitium · Volume 1 (2026) · #01
Published 31 July 2026
Ecology & Environmental Organisation

Experiments with Cistus albidus L. suggest that water carrying gravel and sediment can help unlock hard-coated seeds, challenging a fire-centred view of Mediterranean shrub regeneration.

Note:
This Research Commentary reflects on findings previously published in Ecological Processes. It presents an interpretive perspective and does not report new experimental data.

Author disclosure: Daniel Raus de Baviera is the first and corresponding author of the study discussed in this commentary.